ABSTRACT
Introduction: Urinary tract infection in pregnancy isassociated with significant morbidity for both the motherand the baby. The aim of this study was to determine thebacterial profile and antibiotic resistance pattern of the urinarypathogens isolated from pregnant women at Mata GujriMemorial Medical College and Hospital, Kishanganj.Material and methods: A total of 267 pregnant womenwith and without symptoms of urinary tract infection wereenrolled as a study subject from October 2016to october2017.Organisms were identified from mid-stream clean catch urinesamples and antibiotic susceptibility was performed usingbacteriological standard tests. Data were collected usingstructured questionnaires and were processed and analyzedusing SPSS for Windows version 16.Results: Out of 267 pregnant women, 37 were symptomaticand the rest 230 asymptomatic. Bacteriological screening ofurine samples revealed growth of bacteria in 8.5% (7/37) and18.9% (28/230) for symptomatic and asymptomatic pregnantwomen respectively with overall prevalence of 9.5%.The most common isolates detected were E.coli (45.7%)followed by coagulase negative Staphylococcus (17.1%).Gram-negative bacteria showed resistance rates in the rangeof 56.5%-82.6% against trimethoprim/sulfamethoxazole,amoxicillin and ampicillin. Gram positive isolates showedresistant rate ranging from 50-100% against trimethoprimsulphamethoxazole, amoxicillin and ampicillin. Both Grampositive and gram negative bacteria showed high sensitivityagainst Nitrofurantoin with a rate of 82.3% and 87%,respectively. All isolated Gram positive bacterial uropathogenswere sensitive for Amoxicillin-clauvlanic acid.Conclusion: The isolation of bacterial pathogens both fromsymptomatic and asymptomatic pregnant women that areresistance to the commonly prescribed drug calls for an earlyscreening of all pregnant women to urinary tract infection.